Ion Chromatography Standards
Apexbio Technology LLC Ipriflavone (Osteofix) 35212-22-7 1g
Ipriflavone Osteofix is a small-molecule inhibitor targeting bone resorption It is designed to modulate osteoclast-related signaling pathways thereby reducing bone resorptive activity Ipriflavone Osteofix exerts its biological activity primarily through inhibition of osteoclast-mediated bone remodeling In in vitro studies Ipriflavone Osteofix demonstrates inhibition of cellular signaling processes involved in bone mineral loss Based on these pharmacological properties Ipriflavone Osteofix holds research potential in experimental studies of osteoporosis and related bone disorders
Waters Corporation Cation Calibration Standard, Ammonium as NH4, 100 mg/L, 125 mL
Designed for cation analysis by Ion Chromatography, this standard can be used for primary calibration or to prepare second source calibration check standards. It is traceable to NIST Standard Reference Materials, where available, and guaranteed stable for one year, for direct use with ion-exchange chromatography.
- Ammonium as NH4 cation calibration standard 100 mg/L in H2O matrix.
- Used for cation analysis by Ion Chromatography.
- For primary calibration or to prepare second source calibration check standards.
- Traceable to NIST Standard Reference Materials, where available.
- Guaranteed stable for one year.
- Designed for direct use with ion-exchange chromatography.
- Helps align chromatograph for a linear relationship with the solution signal.
- Offers 100 mg/L concentration.
- Inspected and satisfies strict QC process.
Apexbio Technology LLC Trichlormethiazide 133-67-5 1g
Trichlormethiazide is a small-molecule inhibitor targeting the sodium-chloride cotransporter (NCC) It is designed to inhibit NCC in the distal convoluted tubules thereby decreasing sodium and chloride reabsorption and modulating fluid and electrolyte balance Trichlormethiazide exerts its biological activity primarily through inhibition of sodium and chloride reabsorption Based on these pharmacological properties Trichlormethiazide holds research potential in studies of electrolyte and fluid regulation hypertension-related pathophysiology and renal function as well as the investigation of renal tubular sodium handling and screening interventions affecting nephron sodium transport processes in biological models
Apexbio Technology LLC Amsacrine 51264-14-3 1g
Amsacrine (CAS 51264-14-3) also known as m-AMSA is a small-molecule inhibitor of DNA topoisomerase II It is widely used as an antineoplastic agent in biomedical research particularly for investigating the treatment of lymphomas and acute leukemias Amsacrine exhibits cytotoxic effects across various cancer cell lines with reported IC50 values of 190 2 27 4 ng/ml 46 1 3 9 ng/ml and 22 6 3 1 ng/ml in HT1376 RT112 and RT4 bladder cancer cells and 11 8 2 0 ng/ml 5 0 0 4 ng/ml and 11 7 1 5 ng/ml in the 833K Susa and GH testicular cancer cell lines respectively Testicular cancer cell lines display greater sensitivity to Amsacrine-induced inhibition than bladder cancer cell lines This compound is valuable for studying DNA damage mechanisms and the cellular response to topoisomerase II inhibition
Inorganic Ventures 1000µg/mL FLUORIDE 500mL
Matrix: Water (H2O), Starting Material: NaF, Analyte: F- 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Apexbio Technology LLC Asenapine 85650-56-2 1g
Asenapine (CAS 85650-56-2) is a small-molecule psychotropic agent characterized by high-affinity antagonism at multiple neurotransmitter receptors including several serotonin (5-HT) dopamine noradrenaline and histamine receptor subtypes (with reported pK sub i /sub values in the high nanomolar to sub-nanomolar range such as 8 60 8 40 10 15 9 75 and 10 46) This broad receptor antagonism profile underlies its capacity to modulate neurotransmission in various central nervous system pathways Asenapine is widely employed in biomedical research to investigate the pharmacological basis of antipsychotic activity and to study the functional roles of monoaminergic and histaminergic signaling in psychiatric and neuropharmacological models
Apexbio Technology LLC Abametapir 1762-34-1 1g
Abametapir (CAS 1762-34-1) is a small-molecule inhibitor targeting metalloproteinases It is designed to inhibit metalloproteinase enzymes involved in the egg hatching and survival processes of lice Abametapir exerts its biological activity primarily through inhibition of metalloproteinases In in vitro assays abametapir demonstrates ovicidal activity with reported IC50 values approximately in the low micromolar range Based on these pharmacological properties abametapir holds research potential in the management of head lice infestations and laboratory studies on ectoparasite enzyme inhibition and resistance development
Apexbio Technology LLC Toltrazuril 69004-03-1 1g
Toltrazuril (69004-03-1) is an antiprotozoal compound targeting coccidial parasites It is designed to interfere with mitochondrial energy metabolism and the division of protozoan parasites thereby inhibiting parasite proliferation Toltrazuril exerts its biological activity primarily through disruption of mitochondrial function in protozoa In in vitro studies toltrazuril demonstrates inhibitory activity against coccidial parasites with reported IC50 values typically ranging from 0 02 to 0 3 g/mL depending on testing conditions and parasite species Based on these pharmacological properties toltrazuril holds research potential in experimental investigations of antiprotozoal mechanisms parasite-host interactions and therapeutic evaluations against protozoan pathogens
Apexbio Technology LLC Ethionamide 536-33-4 1g
Ethionamide (CAS 536-33-4) is a small-molecule inhibitor targeting enoyl-acyl carrier protein reductase (InhA) It is designed to inhibit mycolic acid biosynthesis thereby disrupting bacterial cell-wall integrity Ethionamide exerts its biological activity primarily through inhibiting the function of InhA In in vitro studies Ethionamide demonstrates antimycobacterial activity against Mycobacterium tuberculosis with reported MIC values typically ranging from approximately 0 3 to 2 5 g/mL Based on these pharmacological properties Ethionamide holds research potential in studies of multidrug- or extensively drug-resistant tuberculosis
Apexbio Technology LLC Thiabendazole 148-79-8 1g
Thiabendazole (CAS 148-79-8) is a small-molecule inhibitor targeting microtubule assembly It is designed to disrupt microtubule formation thereby altering fungal cell cycle progression Thiabendazole exerts its biological activity primarily through inhibition of microtubule assembly In in vitro studies thiabendazole demonstrates inhibition of CYP1A2 enzyme activity with an IC50 value ranging from 0 5 to 1 M in enzymatic interaction assays Based on these pharmacological properties thiabendazole holds research potential in metabolic enzyme studies and environmental toxicology investigations
Apexbio Technology LLC Curdlan 54724-00-4 1g
Curdlan (CAS 54724-00-4) is a linear -1 3-glucan polysaccharide synthesized by bacteria It is notable for its high water solubility and ability to form thermally stable gels Mechanistically curdlan interacts with immune cell receptors such as Dectin-1 modulating cellular signaling pathways involved in innate immunity Experimental studies indicate it can stimulate macrophage activation and cytokine production suggesting immunomodulatory and potential antitumor activities In biomedical research curdlan is utilized to investigate innate immune responses as well as for its application as a gel matrix in drug delivery and tissue engineering studies
Apexbio Technology LLC NSC 8751 107-93-7 1g
NSC 8751 (CAS 107-93-7) is a straight-chain fatty acid featuring an unbranched aliphatic structure Small molecules in this class are known to modulate cellular metabolism by acting as substrates or inhibitors of various enzymes involved in lipid metabolic pathways NSC 8751 has been utilized as a research tool to study fatty acid uptake -oxidation and related signaling processes in cellular systems Its role in elucidating mechanisms of metabolic regulation makes it valuable in experimental models investigating lipid metabolism energy homeostasis and associated pathologies
Apexbio Technology LLC Diethylstilbestrol 56-53-1 1g
Diethylstilbestrol (56-53-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase type 2 (HSD11B2) and interacting with estrogen receptors It is designed to modulate hormonal signaling and cellular steroid metabolism thereby regulating processes such as apoptosis and autophagy Diethylstilbestrol exerts its biological activity primarily through the inhibition of HSD11B2 and modulation of estrogen receptor-mediated signaling In cell-based studies Diethylstilbestrol induces oxidative DNA damage and triggers apoptotic responses in spermatogonial stem cells as well as promotes autophagy in thymic cells Based on these pharmacological properties Diethylstilbestrol holds research potential in exploring estrogen receptor-mediated signaling hormone-regulated molecular events apoptosis pathways and autophagy mechanisms in vitro
Apexbio Technology LLC Tylosin phosphate 1405-53-4 1g
Tylosin phosphate (CAS 1405-53-4) is a small-molecule inhibitor targeting bacterial ribosomal subunits It is designed to interfere with bacterial translation thereby inhibiting bacterial protein synthesis Tylosin phosphate exerts its biological activity primarily through binding to ribosomal subunits of Gram-positive bacteria In in vitro studies tylosin phosphate demonstrates inhibitory activity with reported IC50 values generally ranging between 0 5 5 g/mL depending on bacterial strain and assay conditions Based on these pharmacological properties tylosin phosphate holds research potential in studies of antibiotic resistance mechanisms antibacterial spectrum evaluation and as an antibiotic additive to explore growth promotion and therapeutic utility in poultry swine and bovine models